abstract：:Healthy humans regulate daily water balance remarkably well across their lifespan despite changes in biological development and exposure to stressors on hydration status. Acute or chronic body water deficits result when intakes are reduced or losses increase, but day-to-day hydration is generally well maintained so lo...

journal_title：Nutrition reviews

authors： Sawka MN,Cheuvront SN,Carter R 3rd

更新日期：2005-06-01 00:00:00

abstract：:A group of heterocyclic amines that are mutagens and rodent carcinogens form when meat is cooked to medium and well-done states. The precursors of these compounds are natural meat components: creatinine, amino acids, and sugars. Defined model systems of dry-heated precursors mimic the amounts and proportions of hetero...

journal_title：Nutrition reviews

authors： Knize MG,Felton JS

更新日期：2005-05-01 00:00:00

abstract：:Epidemiological studies have suggested an association between vitamin C (and other antioxidant vitamins) and cancer risk. However, the mechanisms accounting for prevention have not been extensively investigated. In skin, vitamin C (ascorbic acid) exerts different biological roles, including photoprotective effects and...

journal_title：Nutrition reviews

authors： Catani MV,Savini I,Rossi A,Melino G,Avigliano L

更新日期：2005-03-01 00:00:00

abstract：:Patients in the intensive care unit are at high risk of glutamine depletion and subsequent complications. Several controlled studies and a meta-analysis have concluded that glutamine supplementation has beneficial effects on the clinical outcome of critically ill and surgical patients. These results may be explained b...

journal_title：Nutrition reviews

authors： Coëffier M,Déchelotte P

更新日期：2005-02-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a major cause of visual impairment in the United States. Currently there is no effective cure for this disease. Risk factors include decreased lutein and zeaxanthin status and obesity. Obesity is also an increasing public health concern. The alarming increase in the prevalence...

journal_title：Nutrition reviews

authors： Johnson EJ

更新日期：2005-01-01 00:00:00

abstract：:In recent years it has been suggested that patients with celiac disease can be adequately followed up on the basis of merely clinical and serological response to a gluten-free diet. Thus, a duodenal biopsy some months after commencement of a gluten-free diet would no longer be necessary. We report here the case of a c...

journal_title：Nutrition reviews

authors： Biagi F,Campanella J,Martucci S,Pezzimenti D,Ciclitira PJ,Ellis HJ,Corazza GR

更新日期：2004-09-01 00:00:00

abstract：:Observational studies have found that diets rich in whole-grain foods are associated with improved insulin sensitivity. The improved insulin sensitivity may be mediated in part by magnesium and dietary fiber, two nutrients found in whole-grain foods. By incorporating whole-grain foods into the diet, therefore, insulin...

journal_title：Nutrition reviews

authors： McKeown NM

更新日期：2004-07-01 00:00:00

abstract：:Differences among ethnic and racial groups in obesity-related traits have been clearly established in the scientific literature. To explore the genetic component underlying these differences, the genetic admixture approach has been used. In this approach, ancestry informative genetic markers are used to estimate a qua...

journal_title：Nutrition reviews

authors： Fernández JR,Shiver MD

更新日期：2004-07-01 00:00:00

abstract：:This paper examines the speed of change in diet, activity, and obesity in the developing world, and notes potential exacerbating biological relationships that contribute to differences in the rates of change. The focus is on lower- and middle-income countries of Asia, Africa, the Middle East, and Latin America. These ...

journal_title：Nutrition reviews

authors： Popkin BM

更新日期：2004-07-01 00:00:00

abstract：:Milk intake is considered an important determinant of peak bone mass; consequently, its intake early in life may decrease risk of osteoporotic fractures later. Using the milk history questionnaire, many investigators have conducted retrospective cross-sectional studies and have determined a positive effect of milk int...

journal_title：Nutrition reviews

authors： Vatanparast H,Whiting SJ

更新日期：2004-06-01 00:00:00

abstract：:Among the numerous polyphenols isolated from green tea, the catechin EGCG predominates and is the target of anticancer research. But studies suggest that EGCG and other catechins are poorly absorbed and undergo substantial biotransformation to species that include glucuronides, sulfates, and methylated compounds. Nume...

journal_title：Nutrition reviews

authors： Moyers SB,Kumar NB

更新日期：2004-05-01 00:00:00

abstract：:Manganese is an essential nutrient that also may be toxic at high concentrations. Subjects chronically exposed to manganese-laden dust in industrial settings develop neuropsychological changes that resemble Parkinson's disease. Manganese has been proposed as an additive to gasoline (as a replacement for the catalytic ...

journal_title：Nutrition reviews

authors： Finley JW

更新日期：2004-04-01 00:00:00

abstract：:Insulin resistance is the core metabolic abnormality in type 2 diabetes. Its high prevalence and its association with dyslipidemia, hypertension, hyperinsulinemia, and high coronary and cerebrovascular mortality put it in the forefront as the plausible target for aggressive intervention. Measurements of insulin sensit...

journal_title：Nutrition reviews

authors： Monzillo LU,Hamdy O

更新日期：2003-12-01 00:00:00

abstract：:The role of maternal vitamin A supplements in decreasing the risk of mother-to-child HIV transmission has been examined in sub-Saharan Africa. Overall, there is no reduction in either mortality or HIV transmission in two recent studies. Contrary to expectations, one study reported an increased risk of transmission usi...

journal_title：Nutrition reviews

authors： Stephensen CB

更新日期：2003-08-01 00:00:00

abstract：:Isoflavones present in soy may have risk and benefits to human health. Human gut microflora have been shown to exert metabolic activities on isoflavones, which influences bioavailability and bioactivity. Absorption of isoflavones is likely to occur in the small intestine where there is a diverse range of microfloral s...

journal_title：Nutrition reviews

authors： Turner NJ,Thomson BM,Shaw IC

更新日期：2003-06-01 00:00:00

abstract：:This article reviews the environmental impact of genetically modified crops through discussion of environmental risk assessment and includes several case studies. Influence of European regulatory and political issues is considered. ...

journal_title：Nutrition reviews

authors： Kuiper H

更新日期：2003-06-01 00:00:00

abstract：:Attention to the different types of carbohydrates and their role in health and disease is relatively recent. FAO and WHO jointly published a report on carbohydrates in human nutrition in 1998, with a number of recommendations about increasing carbohydrate intake as a sound approach to the prevention of obesity. The gl...

journal_title：Nutrition reviews

authors： Nantel G

更新日期：2003-05-01 00:00:00

abstract：:Worldwide, the number of individuals who are co-infected with human immunodeficiency virus (HIV) and tuberculosis is increasing greatly. The "triple trouble" of HIV and tuberculosis infection and malnutrition may put those infected at greater risk than those with any of the three conditions alone. Further investigatio...

journal_title：Nutrition reviews

authors： van Lettow M,Fawzi WW,Semba RD

更新日期：2003-03-01 00:00:00

abstract：:Obesity is an established risk factor for postmenopausal, but not premenopausal, development of breast cancer. Evidence for a positive association between obesity and breast cancer mortality is mounting. Avoiding adult weight gain and maintaining a healthy body weight may contribute importantly to decreasing breast ca...

journal_title：Nutrition reviews

authors： Barnett JB

更新日期：2003-02-01 00:00:00

abstract：:The antimicrobial peptide hepcidin has been implicated in the regulation of iron homeostasis. Hepcidin is theorized to be a key link between body iron stores and the appropriate modulation of dietary iron absorption. ...

journal_title：Nutrition reviews

authors： Wessling-Resnick M

更新日期：2002-11-01 00:00:00

abstract：:Body adiposity is known to be carefully regulated and to remain relatively stable for long periods of time in most mammalian species. This review summarizes old and recent data implicating insulin and leptin as key circulating signals to the central nervous system, particularly the ventral hypothalamus, in communicati...

journal_title：Nutrition reviews

authors： Porte D Jr,Baskin DG,Schwartz MW

更新日期：2002-10-01 00:00:00

abstract：:The Metabolic Syndrome, also known as Syndrome X, refers to a constellation of atherosclerotic risk factors, including insulin resistance, hyperinsulinemia, dyslipidemia, essential hypertension, and abdominal obesity. We review four major published studies involving animals and humans that may be linked together in a ...

journal_title：Nutrition reviews

authors： Roth JL,Mobarhan S,Clohisy M

更新日期：2002-10-01 00:00:00

abstract：:Glucokinase plays a major role in the control of hepatic glucose uptake and storage as glycogen. Small amounts of fructose-1-phosphate, in the presence of relatively high glucose levels, markedly stimulate glucokinase through a novel mechanism of regulation involving dissociation from a regulatory protein and transloc...

journal_title：Nutrition reviews

authors： Watford M

更新日期：2002-08-01 00:00:00

abstract：:Epidemiologic studies have demonstrated an increased incidence of kidney stones in individuals with low calcium intake. More recently, a 5-year clinical study found the recurrence of kidney stones was higher in stone-formers on a low dietary calcium treatment. Considering these important new findings, and the known ad...

journal_title：Nutrition reviews

authors： Martini LA,Heilberg IP

更新日期：2002-07-01 00:00:00

abstract：:International nutrition will become increasingly concerned with evaluation of nutritional status at the community level to diagnose situations of risk for nutrient deficits and excesses, and to monitor the impact of remedial interventions. Advances in biologic concepts and technology (particularly miniaturization of a...

journal_title：Nutrition reviews

authors： Solomons NW

更新日期：2002-05-01 00:00:00

abstract：:The burden of maternal morbidity and mortality in developing countries is high. Each year, 600,000 women die from pregnancy-related causes and 62 million women suffer from morbidity and complications of pregnancy. The extent to which maternal nutrition can improve maternal health and survival is not well understood. E...

journal_title：Nutrition reviews

authors： Christian P

更新日期：2002-05-01 00:00:00

abstract：:Dietary fat facilitates the utilization of carotenoids and, based on serum beta-carotene or retinol responses following ingestion of meals containing carotene and fat sources, it has been reported that the amount of fat required in a meal may be minimal (approximately 3-5 g). However, the dietary fat requirement for o...

journal_title：Nutrition reviews

authors： Ribaya-Mercado JD

更新日期：2002-04-01 00:00:00

abstract：:Food fortification is an important strategy to combat iron and zinc deficiency. This review covers the basic concepts of food fortification, as well as its advantages and disadvantages. The main characteristics of the most common zinc and iron compounds used in this procedure are also analyzed. ...

journal_title：Nutrition reviews

authors： Salgueiro MJ,Zubillaga M,Lysionek A,Caro R,Weill R,Boccio J

更新日期：2002-02-01 00:00:00

abstract：:Although body weight is considered to positively affect bones of children and adults, recent studies suggest that overweight and obesity in childhood and adolescence reduce bone mineral content below what would be predicted based on weight and are associated with an increase in incidence of childhood fractures. ...

journal_title：Nutrition reviews

authors： Whiting SJ

更新日期：2002-01-01 00:00:00

abstract：:Among dietary factors implicated in the development of colorectal cancer (CRC), the inverse relationship between vegetable and fruit consumption and CRC risk has long been believed to represent the strongest epidemiologic evidence. However, recently published large prospective studies have produced conflicting results...

journal_title：Nutrition reviews

authors： Kim YI

更新日期：2001-12-01 00:00:00

abstract：:Convincing epidemiologic evidence currently exists for an association between physical activity and the prevention of colon and breast cancer Physical activity may also reduce the risk of cancer at several other sites. With increasing research on this topic, it is apparent that studies of physical activity and cancer ...

journal_title：Nutrition reviews

authors： Friedenreich CM

更新日期：2001-11-01 00:00:00

abstract：:Two recent studies suggest that when consuming a low-calcium diet, low efficiency of calcium absorption (measured as fractional calcium absorption) is a problem in the elderly; this is also an important risk factor for hip fracture. These studies show that elderly women are less able to compensate for low calcium inta...

journal_title：Nutrition reviews

authors： Fleet J

更新日期：2001-10-01 00:00:00

abstract：:Copper transport at the cellular level is achieved by a coordinate series of interactions between passive and active membrane transport proteins, vesicles, and soluble peptides. Knowing the function of each component of this complex network has made the task of delineating the mechanism of intracellular copper homeost...

journal_title：Nutrition reviews

authors： Harris ED

更新日期：2001-09-01 00:00:00

abstract：:Functional genomics, commonly applied to the genes and enzymes involved in metabolism of chemicals, can also be applied to enzymes involved in the metabolism of nutrients. Although in its infancy, genomics can be used to determine relationships between nutrition and toxicology, drug metabolism, and cancer. ...

journal_title：Nutrition reviews

authors： Guengerich FP

更新日期：2001-08-01 00:00:00

abstract：:A recent study indicates that lowering homocysteine with folic acid and vitamin B6 significantly reduces the incidence of abnormal exercise electrocardiography tests and thus decreases the risk of atherosclerotic disease. Questions about study design and sample size, however, suggest that this conclusion may be premat...

journal_title：Nutrition reviews

authors： Miller JW

更新日期：2001-07-01 00:00:00

abstract：:Combining data from two large-scale prospective observational studies in women and men, investigators link the consumption of fruits and vegetables to the risk of ischemic stroke. Of interest is their breakdown of these foods into cruciferous vegetables and citrus fruit juice, which confer the greatest protection. ...

journal_title：Nutrition reviews

authors： Feldman EB

更新日期：2001-01-01 00:00:00

abstract：:The lipoprotein lipase gene is highly polymorphic, and several common mutations have been associated with an increased atherogenic lipid profile. One of these, Asn291Ser, was also found to be associated with increased ischemic heart disease in women. More recently, this same mutation, present in approximately 5% of th...

journal_title：Nutrition reviews

authors： Ordovas JM

更新日期：2000-10-01 00:00:00

abstract：:Continually expanding evidence has moved inexorably toward establishing key functions for cellular retinol-binding protein (CRBP) in retinoid metabolism. These experimental data integrate into a model of CRBP as a chaperone that protects retinol from the cellular milieu and interacts with certain retinoid-metabolizing...

journal_title：Nutrition reviews

authors： Napoli JL

更新日期：2000-08-01 00:00:00

abstract：:We present a case of an African-American child with vitamin D-deficient rickets. In addition to being solely breast-fed for the period of 1 year, he resided in New England, where exposure to ultraviolet light is limited owing to its northern latitude and long cold winters. He presented with classical signs of nutritio...

journal_title：Nutrition reviews

authors： Fitzpatrick S,Sheard NF,Clark NG,Ritter ML

更新日期：2000-07-01 00:00:00

abstract：:Vitamin E per unit serum cholesterol has been found to correlate with memory performance in a recent analysis of data from the Third National Health and Nutrition Examination Survey. Because vitamin E is thought to be protective against vascular disease, this finding is consistent with the growing body of evidence tha...

journal_title：Nutrition reviews

authors： Miller JW

更新日期：2000-04-01 00:00:00